BDBM31883 9-cis-retinoic acid (9cRA)::ALL-TRANS-RETINOIC ACID::AT-RA::Atralin::CHEMBL38::MLS000028588::SMR000058245::TRETINOIN::Vitamin A acid::[3H]RA::[3H]Retinoic acid::[3H]Vitamin A acid::[3H]tretinoin::all-trans retinoic acid::cid_444795
SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
InChI Key InChIKey=SHGAZHPCJJPHSC-YCNIQYBTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 49 hits for monomerid = 31883
Affinity DataKi: 0.0400nMAssay Description:Agonistic activity of the compound towards retinoic acid receptor-gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of [3H]-RA to binding Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity towards human Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity to retinoic acid receptor (RAR) gamma using [3H]-CD 367 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Binding affinity of the compound was determined for Retinoic acid receptor betaMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Compound was tested for binding affinity against retinoic acid receptor using 5 nM of [3H]-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity for retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Transcriptional activation in CV-1 cells expresing human Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 19nMAssay Description:Binding constant for baculovirus-expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Transcriptional activation in CV-1 cells expressing Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Binding affinity against retinoic Acid gamma receptor using [3H]- -9-cis-Retinoic Acid in competitive binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of binding to murine Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Binding affinity against retinoic Acid gamma receptors cotransfected into CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Binding affinity for baculovirus-expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Apparent binding constant against Retinoic acid receptor gamma in HeLa cell GAl-4 transactivation assayMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Inhibition of [3H]-ATRA binding to baculovirus expressed Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Dissociation constant for binding to Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of binding to retinoid A receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Effective concentration for retinoic acid receptor RAR alpha transcriptional activationMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Ability to displace 3[H]-(all-E)-retinoic acid (5 nM) from Retinoic acid receptor gamma using transactivation assayMore data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Inhibition of [3H]-RA binding to retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:In vitro binding affinity for Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of Retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Binding affinity against Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataKd: 16nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
Affinity DataKd: 0.200nMAssay Description:Dissociation constant for Retinoic acid receptor gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.200nMAssay Description:Activity at human RARgamma ligand binding domain expressed in COS7 cells cotransfected with Gal4-DBD assessed as transcriptional activation after 16 ...More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity for retinoic acid receptor RAR gamma in transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation of retinoic acid receptor RAR gammaMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Transcriptional activation for RAR gamma receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 50.1nMAssay Description:Activity at RARgamma expressed in mouse NIH3T3 cells by R-SAT assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]-9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
Affinity DataKd: 17nMAssay Description:Inhibition of [3H]-9-cis-RA binding to mouse Retinoid X receptor RXR betaMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Binding affinity towards retinoic acid receptor gamma was determined using [3H]-ATRA (5 nM) as radioligandMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 0.220nMAssay Description:Transactivation of mouse Gal4-fused RARgamma-LBD expressed in COS-7 cells after 1 day by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Transactivation of GST-tagged RARgamma LBD (unknown origin) assessed as fluorescein-labelled coactivator peptide recruitment measured after 4 hrs by ...More data for this Ligand-Target Pair
Affinity DataKd: 18nMAssay Description:Inhibition of [3H]ATRA binding to baculovirus expressed RAR gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Mus musculus)
University Of Alabama At Birmingham
Curated by ChEMBL
University Of Alabama At Birmingham
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Transactivation of GAL4-fused mouse RARgamma-LBD expressed in COS-7 cells after 24 hrs by bright-Glo reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity RARgamma (unknown origin) assessed as induction of receptor transactivationMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Agonist activity RARgamma (unknown origin) assessed as induction of receptor transactivationMore data for this Ligand-Target Pair